Cell Biology and Metabolic Disorder

research domains

Cell Biology and Metabolic Disorder

This department engages in investigation of mammalian cells leveraged as exigent model system to find application in various important aspects like study of various diseases situations (metabolic disorders, cancer, COPD, myocardial infarction etc); biomolecular therapeutics; development of vaccines; elucidation of drug delivery mechanism etc. Study on intracellular signalling pathways and involvement of subcellular organelles unravels yet-unidentified facts on cellular machineries leading to a better mechanistic understanding of specific physiological conditions. The department, with its ‘state-of-the-art’ facility, aspires to achieve, through appropriate translational innovations, significant contributions towards disease management and improvement of public health.

Diabetes is a disease that occurs when your blood glucose, also called blood sugar, is too high. Blood glucose is the main source of energy and comes from the food we eat. Diabetes is a chronic disease that occurs when the pancreas is no longer able to produce insulin, or when the body cannot make good use of the insulin it produces. Insulin, a hormone made by the pancreas, helps glucose from food get into our cells to be used for energy. Sometimes our body doesn’t make enough—or any—insulin or doesn’t use insulin well. Glucose then stays in our blood and doesn’t reach our cells. There are three main types of diabetes – type 1, type 2 and gestational.

Scientists at I3TK will address the issue by developing novel therapeutic intervention to treat diabetic conservancies. Pathophysiological models will be established ‘in-vitro’ and ‘in-vivo’ and efficacy of strategies will be investigated. Cost-effective disease-associated financial burden of community.