Bharat Biotech’s Covaxin has immunological memory to Covidand its variants of concern for
at least up to six months, National Institute of Immunology (NII) director in-charge Pushkar
Sharma said on Monday. It means the vaccine can provide protection from the virus for a
minimum of that duration.
Immunological memory is the ability of the immune system to respond more rapidly and
effectively to pathogens that have been encountered previously.
“The inactivated virus vaccine BBV152/Covaxin elicits robust cellular immune memory to
SARS-CoV-2 and variants of concern- Delta, Alpha, Beta and Gamma, which persist at least
up to 6 months,” Sharma said during the annual general body meeting of the society of NII.
The meeting, held on Sunday, was presided over by Union Minister for Science and
Technology Jitendra Singh. Sharma presented the work done by the institution in
understanding fundamental processes that regulate inflammation, pathogenesis, ageing and
immune response, the Science and Technology Ministry said in a statement.
He mentioned that the focus has been on various areas of research, including infection and
immunity, molecular design, gene regulation and reproduction and development. In these
areas, cutting edge research in modern biology is being carried out employing multiple
overlapping disciplines of modern biology. He mentioned that significant efforts have been
made towards transitional research specifically for SARS-CoV-2 vaccine.
NII has also provided services for COVID-19 research. Under this programme, 65 Medical
laboratory technologists (MLTs)/lab technicians were trained in various aspects of COVID-19.
There have been more than 30,000 samples screened so far and the positive samples have
been sent for genome sequencing.
Sharma further elaborated that NII has also developed a collagen based herbal formulation
for osteoarthritis (OA). The formulation (SG002) contains a bioactive collagen peptide and
alcoholic extract of two exotic Himalayan plants. He added that the institute is also part of the
Indo-European Consortium for Next Generation Influenza Vaccination.
The institution is part of the group working on COBRA (Computationally Optimized Broadly
Reactive Antigen) vaccine.
It will be developed by analysing the sequence of influenza strains over a decade covering
seasonal and pandemic strains. Based on the research from the last two decades it is
suggested that COBRA vaccine is expected to provide protection against seasonal flu, all the
pandemic strains of flu and any emerging flu strains, the statement said.
