{"id":10538,"date":"2021-08-04T06:37:43","date_gmt":"2021-08-04T06:37:43","guid":{"rendered":"https:\/\/i3tk.org\/demo2\/?p=10538"},"modified":"2021-08-04T06:39:06","modified_gmt":"2021-08-04T06:39:06","slug":"study-new-onset-diabetes-in-covid-biggest-risk-factor-for-black-fungus","status":"publish","type":"post","link":"https:\/\/i3tk.org\/demo2\/world-news\/study-new-onset-diabetes-in-covid-biggest-risk-factor-for-black-fungus\/","title":{"rendered":"Study: New-onset diabetes in Covid biggest risk factor for black fungus"},"content":{"rendered":"\n

Ahmedabad: Diabetes was the undisputed, most significant risk factor for deadly mucormycosis<\/a> that plagued Covid-19<\/a> patients in the lethal second wave.<\/p>\n\n\n\n

Interim analysis of a local case control study of black fungus<\/a> has now revealed that new onset of diabetes was found to be a far more significant risk factor than pre-existing diabetes as well!<\/p>\n\n\n\n

A study of 300 subjects, which include 234 Covid-19 patients and 64 mucormycosis patients with history of Covid-19, was conducted at Sterling Hospital<\/a> post second wave to understand the risk factors for mucormycosis in Covid-19 patients.<\/p>\n\n\n\n

25% of Covid patients detected with new-onset diabetes in Guj<\/strong>
The biggest takeaway of the interim analysis of the study is that patients in whom diabetes was unmasked during Covid-19 illness had a significantly higher probability of getting black fungus than patients who had a known past history of diabetes,\u201d said infectious diseases specialist Dr Atul Patel. He is member of Gujarat Covid-19 task force and one of 30-authors of the global recommendations for mucormycosis treatment.<\/p>\n\n\n\n

Experts say that nearly 25% Covid-19 patients were detected with new onset diabetes in the state. This includes Covid-19 induced diabetes triggered by severe pancreatic inflammation, stress, steroid treatment or unknown diabetes detected during pandemic illness.<\/p>\n\n\n\n

\u201cOther important findings revealed by the interim analysis include that steroids, tocilizumab and even oxygen were not significant risk factors,\u201d said Dr Patel.<\/p>\n\n\n\n

Dr Patel said probability value of new onset diabetes for black fungus was found to be less than 0.001 while that of diabetes was less than 0.156. Here, lower the probability value means higher risk factor. In fact, p- value lower than 0.05 is considered significant.<\/p>\n\n\n\n

\u201cNew onset diabetes in Covid-19 as a risk factor will now be studied in 1,000 MM patients across 29 centres across India to give better prevention, intervention and treatment guides for future cases especially during the pandemic,\u201d said Dr Patel.<\/p>\n\n\n\n

The findings are significant as estimated 25% black fungus patients had history of new onset diabetes during Covid-19. Dr Bela Prajapati, professor and head of the ENT department at Civil Hospital, said of 819 mucormycosis patients treated in past two months, 192 or 23% recorded no prior history of diabetes. \u201cThese patients acquired blood sugar after their Covid-19 infection,\u201d she said.
Likewise, at Sola Civil Hospital<\/a>, the figure of such patients was about 25-30%, said Dr Neena Bhalodia, head of the ENT department. \u201cAfter the second wave of the pandemic, several young patients who had tested diabetic. Covid-19 and it\u2019s treatment may have been responsible as steroids used in the treatment spiked blood sugar,\u201d she said.<\/p>\n\n\n\n

Dr Neeraj Suri, ENT surgeon at Gandhinagar Civil Hospital<\/a>, said that not all patients who tested diabetic after Covid-19 had mucormycosis. \u201cThe fungal infection was a sum of several factors including age, severity, and comorbidities among others. Some mucormycosis patients didn\u2019t even have diabetes even as they had recovered from Covid. But the presence of blood sugar surely played a big role in the prevalence of fungal infection that fed off the sugar,\u201d she said.<\/p>\n\n\n\n

Dr Rajesh Vishwakarma, a city-based ENT surgeon, said that not all patients of mucormycosis had diabetes only after Covid-19. \u201cIt is also possible that the patients might have borderline diabetes which got aggravated due to Covid-19 and got detected as part of the medical reports,\u201d he said.<\/p>\n\n\n\n

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